PUBLICATIONS
VERMAAK I., VILJOEN A.M., HAMMAN J.H. 2011. Natural products in anti-obesity therapy. Natural Product Reports, 28:1493-1533.
TARIRAI C., ENSLIN G.M., STEENEKAMP J.H. AND HAMMAN J.H. 2011. Moulded cross-linked chitosan matrix systems for controlled drug release. Pharmaceutical Development and Technology, 16(4):295-301.
VERMAAK I., HAMMAN J.H. AND VILJOEN A.M. 2011. Hoodia gordonii: An up-to-date review of a commercially important anti-obesity plants. Planta Medica, 77:1149-1160.
JAMBWA N.T., VILJOEN, A.M., HAMMAN J.H. 2011. Matrix forming excipients from natural origin for controlled release matrix type tablets. Journal of Drug Delivery Science and Technology, 21(5):433-439.
VERMAAK I., VILJOEN A.M., CHEN W., HAMMAN J.H. 2011. In vitro transport of the steroidal glycoside P57 from H. gordonii across porcine intestinal and buccal tissue. Phytomedicine, 18:783-787.
HAMMAN J.H. 2010. Chitosan based polyelectrolyte complexes as potential carrier materials in drug delivery systems. Marine Drugs, 8:1305-1322.
LU Z., CHEN W., VILJOEN A., AND HAMMAN J. 2010. Effect of sinomenine on the in vitro intestinal epithelial transport of selected compounds. Phytotherapy Research, 24:211-218.
VERMAAK I., HAMMAN J.H. AND VILJOEN A.M. 2010. High performance thin layer chromatography as a method to authenticate Hoodia gordonii raw material and products. South African Journal of Botany, 76:119-124.
TARIRAI C., ENSLIN G.M., STEENEKAMP J.H. AND HAMMAN J.H. 2010. Moulded cross-linked chitosan matrix systems for controlled drug release, Pharmaceutical Development and Technology, in press.
LU Z., CHEN W. AND HAMMAN J.H. 2010. Chitosan-polycarbophil interpolyelectrolyte complex as a matrix former for controlled release of poorly water-soluble drugs. Drug Development and Industrial Pharmacy, 36:539-546.
HAMMAN, J.H. AND STEENEKAMP, J.H. 2010. Oral peptide drug delivery: the quest for ways to overcome barriers. In: Peptide drug discovery and development. Translational research in academia and industry. Castanho, M., Santos, C. eds., Wiley-VCH Verlag GmbH & Co, Germany. (invited for publication).
VERMAAK I., VILJOEN A.M., HAMMAN J.H., BARANSKA M. 2010. The potential application of FT-Raman spectroscopy for the quantification and mapping of the steroidal glycoside P57 in Hoodia gordonii. Phytochemistry Letters, 3:156-160.
TARIRAI C., VILJOEN A.M. AND HAMMAN J.H. 2010. Herb-drug pharmacokinetic interactions reviewed. Expert Opinion in Drug Metabolism and Toxicity, 6(12):1-24.
VERMAAK I., VILJOEN A.M., HAMMAN J.H., BARANSKA M. 2010. The potential application of FT-Raman spectroscopy for the quantification and mapping of the steroidal glycoside P57 in Hoodia gordonii. Phytochemistry Letters, 3:156-160.
CHEN W., LU Z., VILJOEN A. AND HAMMAN J. 2009. Intestinal drug transport enhancement by Aloe vera. Planta Medica, 75:587-595.
BENEKE CE, VILJOEN AM, AND HAMMAN JH. 2009. Polymeric plant-derived excipients in drug delivery. Molecules, 14:2602-2620.
VERMAAK I., VILJOEN A.M., HAMMAN J.H. AND VAN VUUREN S.F. 2009. The effect of simulated gastrointestinal conditions on the antimicrobial activity and chemical composition of indigenous South African plant extracts. South African Journal of Botany, 75:594-599.
VERMAAK I., VILJOEN A.M., HAMMAN J.H. AND VAN VUUREN S.F. 2009. Effect of simulated gastrointestinal conditions and epithelial transport on extracts of Green tea and Sage. Phytochemistry Letters, 2:166-170.
OJEWOLE, E., MACKRAJ, I., AKHUNDOV, K., HAMMAN, J., VILJOEN, A. AND GOVENDER T. 2009. Exploring the effect of aloe vera gel on the buccal permeability of didanosine: permeability and histomorphological studies. Journal of Pharmacy and Pharmacology, 61(Supplement 1):A34-A35.
BROWN L., HEYNEKE O., BROWN D., VAN WYK J.P.H. AND HAMMAN J.H. 2008. Impact of traditional medicinal plant extracts on antiretroviral drug absorption. Journal of Ethnopharmacology, 119:588-592.
ENSLIN G.M., KOTZÉ A.F. AND HAMMAN J.H. 2008. Intestinal drug absorption enhancers: synergistic effects of combinations. Drug Development and Industrial Pharmacy, 34:1343-1349.
HAMMAN J.H. 2008. Composition and applications of Aloe vera leaf gel. Molecules, 13:1599-1616.
LU Z., CHEN W., OLIVIER E.I. AND HAMMAN J.H. 2006. Matrix polymeric excipients: comparing a novel interpolyelectrolyte complex with hydroxypropylmethylcellulose. Drug Delivery, 15:87-96.
HUANG M.J., DU PLESSIS J., DU PREEZ J., HAMMAN J.H. AND VILJOEN A.M. 2008. Transport of aspalathin, a Rooibos tea flavonoid, across the skin and intestinal epithelium. Phytotherapy Research, 22:699-704.
LU Z., CHEN W., HAMMAN J.H., NI J. AND ZHAI X. 2008. Chitosan-polycarbophil interpolyelectrolyte complex as an excipient for bioadhesive matrix systems to control macromolecular drug delivery. Pharmaceutical Development and Technology, 13:37-47.
HAMMAN, J.H. 2008. Oral drug delivery. Biopharmaceutical Principles, Evaluation and Optimisation. 2nd edition. Content solutions, SA. (ISBN 978-0-620-40122-7).
OLIVIER E.I., DU TOIT D. AND HAMMAN J.H. 2007. Development of an analytical method for the evaluation of N,N-dimethylformamide in dosage form design. Die Pharmazie, 62:735-738.
LU Z., CHEN W. AND HAMMAN J.H. 2007. Chitosan-polycarbophil complexes in swellable matrix systems for controlled drug release. Current Drug Delivery, 4(4):257-263.
HAMMAN J.H., DEMANA P.H. AND OLIVIER E.I. 2007. Targeting receptors, transporters and site of absorption to improve oral drug delivery. Drug Target Insights, 2:71-81.
HAMMAN, J.H. 2007. Oral drug delivery. Biopharmaceutical Principles, Evaluation and Optimisation. Content solutions, SA. (ISBN 0-620-36395-9).
HAMMAN J.H. AND TARIRAI C. 2006. Functional excipients. Chimica Oggi/Chemistry Today, 24(5):57-62.
CHEN W., LU Z., ENSLIN G., OLIVIER E., PILLAY V., STEENEKAMP J. AND HAMMAN J. 2006. Cross-linked chitosan matrix-based multiple-unit drug delivery systems. Journal of Drug Delivery Science and Technology, 15(1):1-6.
JONKER-VENTER C., SNYMAN D., JANSE VAN RENSBURG C., JORDAAN E., SCHULTZ C., STEENEKAMP J.H., HAMMAN J.H. AND KOTZÉ A.F. 2006. Low molecular weight quaternised chitosan (II): In vitro assessment of absorption enhancing properties. Die Pharmazie, 61:301-305.
HAMMAN J.H., ENSLIN G.M. AND KOTZÉ A.F. 2005. Oral Delivery of Peptide Drugs: Barriers and Developments. Biodrugs: clinical immunotherapeutics, biopharmaceuticals and gene therapy, 19(3):165-177.
LU Z., STEENEKAMP J.H. AND HAMMAN J.H. 2005. Cross-linked cationic polymer microparticles: Effect of N-trimethyl chitosan chloride on the release and permeation of ibuprofen. Drug Development and Industrial Pharmacy, 31(3):311-318.
BROWN D., GOOSEN T.C., CHETTY M. AND HAMMAN J.H. 2003. Effect of oral contraceptives on the transport of chlorpromazine across the Caco-2 intestinal epithelial cell line. European Journal of Pharmaceutics and Biopharmaceutics, 56(2):159-165.
HAMMAN J.H., SCHULTZ C.M. AND KOTZE A.F. 2003. N-trimethyl chitosan chloride: Optimum degree of quaternisation for drug absorption enhancement across epithelial cells. Drug Development and Industrial Pharmacy, 29(2):161-172.
SNYMAN D., HAMMAN J.H. AND KOTZE A.F. 2003. Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride. Drug Development and Industrial Pharmacy, 29(1):61-69.
HAMMAN J.H., STANDER M. AND KOTZE A.F. 2002. Effect of the degree of quaternisation of N-trimethyl chitosan chloride on its absorption enhancing properties: In vivo evaluation in rat nasal epithelia. International Journal of Pharmaceutics, 232(1-2):235-242.
SNYMAN D., HAMMAN J.H., Kotze J.S., Rollings J.E. AND KOTZE A.F. 2002. The relationship between the absolute molecular weight and the degree of quaternisation of N-trimethyl chitosan chloride. Carbohydrate Polymers, 50(2):145-150.
JONKER C., HAMMAN J.H. AND KOTZE A.F. 2002. Intestinal paracellular permeation enhancement with quaternized chitosan: in situ and in vitro evaluation. International Journal of Pharmaceutics, 238:205-213.
HAMMAN, J.H. AND KOTZE, A.F. 2002. Paracellular absorption enhancement across intestinal epithelia by N-trimethyl chitosan chloride. In: Chitosan in Pharmacy and Chemistry. R.A.A. Muzzarelli and C. Muzzarelli, eds., Atec, Italy. (ISBN 88-86889-07-0).
KOTZE, A.F. HAMMAN, J.H., SNYMAN, D., JONKER, C. AND STANDER, M. 2002. Mucoadhesive and absorption enhancing properties of N-trimethyl chitosan chloride. In: Chitosan in Pharmacy and Chemistry. R.A.A. Muzzarelli and C. Muzzarelli, eds., Atec, Italy. (ISBN 88-86889-07-0).
HAMMAN J.H. AND KOTZE A.F. 2001. Effect of the type of base and number of reaction steps on the degree of quaternization and molecular weight of N-trimethyl chitosan chloride. Drug Development and Industrial Pharmacy, 27(5):373-380.
HAMMAN J.H., STANDER M., JUNGINGER H.E. AND KOTZE A.F. 2000. Enhancement of paracellular drug transport by N-trimethyl chitosan chloride. STP Pharma Sciences, 10(1):35-38.PUBLICATIONS (BOOKS AND CHAPTERS IN BOOKS)
